EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30)

EORTC Quality of Life Group


Basic description

  • The EORTC QLG has also developed a computerized adaptive testing (CAT) version of the EORTC QLQ-C30.
  • An Item Library was created and offer the possibility to add items from other module(s)
  • The EORTC QLQ-C30 was developed in 1988 and is a core generic questionnaire associated with different disease specific modules.

Validated Modules:

  • Bone metastases EORTC QLQ-BM22
  • Brain cancer EORTC QLQ-BN20
  • Breast cancer EORTC QLQ-BR23
  • Cervical cancer EORTC QLQ-CX24
  • Colorectal cancer EORTC QLQ-CR29
  • Colorectal liver metastases EORTC QLQ-LMC21
  • Elderly Cancer Patients EORTC QLQ-ELD14
  • Endometrial EORTC QLQ-EN24
  • Gastric EORTC QLQ-STO22
  • Head & Neck cancer EORTC QLQ-H&N35
  • Hepatocellular carcinoma EORTC QLQ-HCC18
  • Information EORTC QLQ-INFO25
  • Lung cancer EORTC QLQ-LC13
  • Multiple myeloma EORTC QLQ-MY20
  • Neuroendocrine carcinoid tumours EORTC QLQ-GINET21
  • Ovarian cancer EORTC QLQ-OV28
  • Oesophageal cancer EORTC QLQ-OES18
  • Oesophago-gastric cancer EORTC QLQ-OG25
  • Prostate cancer EORTC QLQ-PR25

Modules that have completed Phase III:

  • Chronic Myeloid Leukaemia (QLQ-CML24)   
  • High-Dose Chemotherapy (QLQ-HDC29)
  • Muscle Invasive Bladder Cancer (QLQ-BLM30)  
  • Ophthalmic Cancer (QLQ-OPT30)   
  • Breast Reconstruction (QLQ-BrR24)   
  • Chronic Lymphocytic Leukaemia EORTC QLQ-CLL16
  • Melanoma (QLQ-MEL38)      
  • Head & Neck Cancer (QLQ-H&N43) - revision of QLQ-H&N35
  • Cholangiocarcinoma and Gallbladder Cancer (QLQ-BIL21)
  • Cancer Related Fatigue (QLQ-FA13)
  • Oral Health (QLQ-OH17)
  • Pancreatic Cancer (QLQ-PAN26)
  • Peripheral Neuropathy (QLQ-CIPN20)
  • Radiation Proctitis (QLQ-PRT23)
  • Spiritual Wellbeing (QLQ-SWB32)
  • Superficial Bladder Cancer (QLQ-BLS24)
  • Testicular Cancer (QLQ-TC26)

Modules in development:

  • Spinal Cord Compression
  • Symptom based questionnaires  
  • Thyroid Cancer (QLQ-THY)   
  • Anal Cancer     
  • Satisfaction with care in outpatients
  • Nasopharyngeal Carcinoma (QLQ-NPC42)
  • Cancer of the Vulva 
  • Sexual Health
  • Chronic Lymphocytic Leukaemia (CLL), Non-Hodgkin’s
  • Lymphoma (NHL) and Hodgkin’s Lymphoma (HL)
  • Communication (QLQ-COMU34)
  • Cancer Cachexia
  • Update of the EORTC QLQ-LC13 Lung module

Access the complete list of modules on the EORTC website

EORTC: European Organization for Research and Treatment of Cancer

Presently Version 3.0 is the most recent version and should be used for all new studies


EORTC Quality of Life Group

© Copyright 1995 EORTC Quality of Life Group. All rights reserved. Version 3.0
To assess quality of life in a wide range of cancer patient populations
Therapeutic area
  • Neoplasms
Therapeutic indication

Generic for Neoplasms

Type of Clinical Outcome Assessment (COA)
  • pro PRO
Original language(s)
  • English
113 translation(s)
Bibliographic reference(s) of the original questionnaire

Aaronson NK, Bullinger M, Ahmedzai S. A modular approach to quality-of-life assessment in cancer clinical trials. Recent Results Cancer Res. 1988;111:231-49

Aaronson NK, Ahmedzai S, Bullinger M, Crabeels D, Estape J, Filiberti AN et al. The EORTC Core Quality of Life Questionnaire : Interim Results of an International Field Study. In: OSOBA D, editor. Effect of Cancer on Quality of Life. Vancouver: 1991: 185-202

Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85:365-76 (PubMed abstract)

Hjermstad MJ, Fossa SD, Bjordal K, Kaasa S. Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire. J Clin Oncol. 1995 May;13(5):1249-54 (PubMed abstract)

King MT. The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res. 1996 Dec;5(6):555-67. Review (PubMed abstract)

Osoba D, Aaronson N, Zee B, Sprangers M, te Velde A. Modification of the EORTC QLQ-C30 (version 2.0) based on content validity and reliability testing in large samples of patients with cancer. The Study Group on Quality of Life of the EORTC and the Symptom Control and Quality of Life Committees of the NCI of Canada Clinical Trials Group. Qual Life Res. 1997 Mar;6(2):103-8 (PubMed abstract)

Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol. 1998 Jan;16(1):139-44 (PubMed abstract)

Bjordal K, de Graeff A, Fayers PM, Hammerlid E, van Pottelsberghe C, Curran D, Ahlner-Elmqvist M, Maher EJ, Meyza JW, Brédart A, Söderholm AL, Arraras JJ, Feine JS, Abendstein H, Morton RP, Pignon T, Huguenin P, Bottomly A, Kaasa S. A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer. 2000 Sep;36(14):1796-807 (PubMed abstract)

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