Functional Reading Independence Index (FRI Index)

Genentech, Inc.


Basic description

Developed in 2013


Genentech, Inc.

© 2015 Genentech, Inc. All rights reserved.
To assess reading function in patients with geographic atrophy (GA) from age-related macular degeneration (AMD)
Therapeutic area
  • Eye Diseases
Therapeutic indication

Macular Degeneration

Age-related macular degeneration
Type of Clinical Outcome Assessment (COA)
  • pro PRO
Original language(s)
  • English for the USA
34 translation(s)
Bibliographic reference(s) of the original questionnaire

Oestreicher N, Bressler NM, Colman SS et al. The Functional Reading Independence Index (FRII): A New Measure of Treatment Benefit in Geographic Atrophy. Investigative Ophthalmology & Visual Science. 2012 March;53(14):5441-5441 (Conference Abstract)

Kimel M, Yu R, Leidy N. The Functional Reading Independence Index (FRI Index) - User Manual (Version 1.2). Evidera. 2015   

Tschosik E, Leidy NK, Kimel M et al. Quantifying functional reading independence in geographic atrophy: the FRI Index. Investigative Ophthalmology & Visual Science. 2015 June;56(7):4789-4789 (Conference Abstract)

Kimel M, Leidy NK, Tschosik E, Dolan C, Souied EH, Varma R, Bressler NM. Functional Reading Independence (FRI) Index: A New Patient-Reported Outcome Measure for Patients With Geographic Atrophy. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6298-6304. doi: 10.1167/iovs.16-20361.(PubMed Abstract)

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