Hand Disability In Systemic Sclerosis - Digital Ulcers (HDISS-DU)

Khanna D; Poiraudeau S; Gelhorn H; Papadakis K; Perchenet L; Mattera MS; Vernon M; Mouthon L; Hunsche E

Distributed by Mapi Research Trust


Distributed by Mapi Research Trust

Basic description

  • Developed in 2011
  • The HDISS-DU has been developed from the Cochin Hand Function Scale (CHFS)

Khanna D; Poiraudeau S; Gelhorn H; Papadakis K; Perchenet L; Mattera MS; Vernon M; Mouthon L; Hunsche E

HDISS-DU® © 2017 Mapi Research Trust
To capture the full spectrum of the impact of digital ulcers in patients and also to assess key symptoms and the impact of the disease on patients’ functioning from the patient perspective
Therapeutic area
  • Skin and Connective Tissue Diseases
  • Rare disease (Orphanet definition)
Therapeutic indication

Scleroderma, Systemic For more information on this rare disease, please consult the following link: Orphanet page

Type of Clinical Outcome Assessment (COA)
  • pro PRO
Original language(s)
  • English for the USA
Bibliographic reference(s) of the original questionnaire

Mouthon, L., Poiraudeau, S., Vernon, M. et al. Psychometric validation of the Hand Disability in Systemic Sclerosis-Digital Ulcers (HDISS-DU®) patient-reported outcome instrument. Arthritis Res Ther 22, 3 (2020) (Full text article)

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Khanna D; Poiraudeau S; Gelhorn H; Papadakis K; Perchenet L; Mattera MS; Vernon M; Mouthon L; Hunsche E

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Mapi Research Trust
27 rue de la Villette
69003 Lyon
Phone: +33 (0)4 72 13 66 66

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Original language(s)

  • English for the USA


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