Derkx H; Griffiths AM; Otley A


Basic description

  • Original IMPACT developed in 1999
  • IMPACT III adapted from the IMPACT-II in 2002

Derkx H; Griffiths AM; Otley A

2002 by the Inflammatory Bowel Disease Working Group
To evaluate disease-related quality of life in children and adolescents with Inflammatory Bowel Disease (Crohn’s Disease and Ulcerative Colitis)
Therapeutic area
  • Digestive System Diseases
Therapeutic indication

Inflammatory Bowel Diseases

Type of Clinical Outcome Assessment (COA)
  • pro PRO
Original language(s)
  • English for North America
64 translation(s)
Bibliographic reference(s) of the original questionnaire

Otley A, Smith C, Nicholas D, Munk M, Avolio J, Sherman PM, Griffiths AM. The IMPACT questionnaire: a valid measure of health-related quality of life in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2002 Oct;35(4):557-63 (PubMed abstract)

Loonen HJ, Grootenhuis MA, Last BF, et al. Measuring quality of life in children with inflammatory bowel disease: the impact-II (NL). Qual Life Res 2002 Feb;11(1):47-56 (PubMed abstract)

Original IMPACT:
Griffiths AM, Nicholas D, Smith C, Munk M, Stephens D, Durno C, Sherman PM. Development of a quality-of-life index for pediatric inflammatory bowel disease: dealing with differences related to age and IBD type. J Pediatr Gastroenterol Nutr 1999; 28:S46-52 (PubMed abstract)

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