Medical Outcome Study-HIV Health Survey (MOS-HIV)


Distributed by Mapi Research Trust


Distributed by Mapi Research Trust

Basic description

The initial MOS-HIV developed in 1991 consisted of 30 items, then the instrument was expanded to 34 items. The final questionnaire consists of 35 items.


WEBINAR: An Author Webinar on the Medical Outcome Study-HIV Health Survey  - Recorded session available here!



MOS-HIV © 1996 The Johns Hopkins University/Albert Wu, MD, MPH. All Rights Reserved.
To evaluate patient outcomes in clinical trials and other studies of people with HIV/AIDS
Therapeutic area
  • Virus Diseases
  • Immune System Diseases
Therapeutic indication

HIV Infections

Type of Clinical Outcome Assessment (COA)
  • pro PRO
Original language(s)
  • English for the USA
Bibliographic reference(s) of the original questionnaire

Wu AW, Rubin HR, Mathews WC, Ware JE Jr, Brysk LT, Hardy WD, Bozzette SA, Spector SA, Richman DD. A health status questionnaire using 30 items from the Medical Outcomes Study. Preliminary validation in persons with early HIV infection. Med Care. 1991 Aug;29(8):786-98 (PubMed Abstract)

Wu AW, Revicki DA, Jacobson D, Malitz FE. Evidence for reliability, validity and usefulness of the Medical Outcomes Study HIV Health Survey (MOS-HIV). Qual Life Res. 1997 Aug;6(6):481-93 (PubMed Abstract)

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Contact and conditions of use



Professor and Director
Center for Health Services & Outcomes Research
Johns Hopkins Bloomberg School of Public Health
624 N Broadway Room 653
Baltimore MD 21205
Phone: +1 (410) 955-6567
Fax: +1 (410) 955-0470
Mobile: +1 (410) 978-1539
E-mail: awu@jhsph.edu

Contact information

Mapi Research Trust
27 rue de la Villette
69003 Lyon
Phone: +33 (0)4 72 13 66 66

Conditions of use

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Review copy

Examination copies can only be used for the limited purpose of examining the suitability of the Questionnaire for subsequent research and/or clinical use, and cannot be used in research or in clinical practice or distributed to others.
You are not authorized to modify, retype, translate, copy or otherwise duplicate the Questionnaire except with the further and prior written permission of Mapi Research Trust / the developers / copyright holders / distributors.


Original language(s)

  • English for the USA


The listed translations may not have undergone a full linguistic validation process and may require further work to be suitable for use in a study. This list is subject to constant changes, therefore please check the status of translations with Mapi Research Trust / the developers / copyright holders / distributors.


Danish for Denmark
Dutch for Belgium (Flemish)
Dutch for the Netherlands
English for Australia
English for the UK
Finnish for Finland
French for Canada*
French for France
German for Germany
Greek for Greece
Indonesian for Indonesia
Italian for Italy
Japanese for Japan
Mandarin for China
Mandarin for Hong-Kong
Portuguese for Brazil
Portuguese for Portugal
Russian for Russia
Spanish for Argentina
Spanish for Mexico
Spanish for Spain*
Spanish for the USA
Swedish for Sweden
Tagalog for the Philippines
Thai for Thailand
Turkish for Turkey
Xhosa for South Africa
* Performed by Mapi

BiblioPRO: you can find information about the Spanish version here - puede encontrar información sobre la versión española aqui

The author has selected Mapi/ICON Language Services as exclusive linguistic validation company to ensure the production of harmonized and consistent language versions.

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Conditions to translate

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More information on translations

Bibliographic references of the translations:
Ichikawa M, Natpratan C. Quality of life among people living with HIV/AIDS in northern Thailand: MOS-HIV Health Survey. Qual Life Res. 2004 Apr;13(3):601-10
Mast TC, Kigozi G, Wabwire-Mangen F, Black R, Sewankambo N, Serwadda D, Gray R, Wawer M, Wu AW. Measuring quality of life among HIV-infected women using a culturally adapted questionnaire in Rakai district, Uganda. AIDS Care. 2004 Jan;16(1):81-94
Scott-Lennox JA, Wu AW, Boyer JG, Ware JE Jr. Reliability and validity of French, German, Italian, Dutch, and UK English translations of the Medical Outcomes Study HIV Health Survey. Med Care 1999;37:908-25
Zander KJ, Palitzsch M, Kirchberger I, Poppinger J, Jägel-Guedes E, Jäger H, von Steinbuchel N, Bullinger M. HIV-infektion und gesundheitsbezogene Lebensqualität: psychometrische prüfung der deutschsprachigen version de "MOS-HIV"-fragebogens zur therapieerfolgskontrolle. (HIV infection and health related quality of life: psychometric testing of the German version of the MOS-HIV questionnaire. AIDS-Forschung (AIFO) 1994;9:241-249

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