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Neuropathy Impairment Score (NIS)

Dyck PJ; Sherman WR; Hallcher LM; Service FJ; Grina LA; Palumbo PJ; Swanson CJ; O'Brien PC

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Basic description

  • Published in 1980
  • Resulted from the revision of the Neuropathy Disability Score (NDS) published in 1980
Authors

Dyck PJ; Sherman WR; Hallcher LM; Service FJ; Grina LA; Palumbo PJ; Swanson CJ; O'Brien PC

Copyright
© 1980 by Peter J Dyck
Objective
To evaluate patient’s muscle strength, sensation and reflexes. The NIS is a composite, quantitative measure of both large- and small-fiber dysfunction.
Therapeutic area
  • Nutritional and Metabolic Diseases
  • Endocrine System Diseases
  • Nervous System Diseases
Therapeutic indication
  • Diabetes Mellitus
  • Diabetic Neuropathies
Type of Clinical Outcome Assessment (COA)
  • clinro ClinRO
Original language(s)
  • English for the USA
Bibliographic reference(s) of the original questionnaire

Dyck PJ, Sherman WR, Hallcher LM et al. Human diabetic endoneurial sorbitol, fructose, and myo-inositol related to sural nerve morphometry. Ann Neurol. 1980; 8:590-596 (PubMed abstract)

Dyck PJ, Kratz KM, Lehman KA, Karnes JL, Melton LJ 3rd, O'Brien PC, Litchy WJ, Windebank AJ, Smith BE, Low PA, et al. The Rochester Diabetic Neuropathy Study: design, criteria for types of neuropathy, selection bias, and reproducibility of neuropathic tests. Neurology. 1991 Jun;41(6):799-807 (PubMed abstract)

Dyck PJ, Turner DW, Davies JL, O'Brien PC, Dyck PJ, Rask CA; rhNGF group. Electronic case-report forms of symptoms and impairments of peripheral neuropathy. Can J Neurol Sci. 2002 Aug;29(3):258-66 (PubMed abstract)

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