Non-motor Symptoms Scale (NMSS)

Chaudhuri KR; International Parkinson’s Disease Non-Motor Symptom Scale Development Group


Basic description

Developed in 2004. The NMS Questionnaire (NMSQuest) was simultaneously developed for screening purposes.


Chaudhuri KR; International Parkinson’s Disease Non-Motor Symptom Scale Development Group

International Parkinson and Movement Disorder Society (MDS)
To assess non-motor symptoms (NMS) in patients with Parkinson's disease (PD)
Therapeutic area
  • Nervous System Diseases
Therapeutic indication

Parkinson Disease

Type of Clinical Outcome Assessment (COA)
  • clinro ClinRO
Original language(s)
  • English for the UK
1 translation(s)
Bibliographic reference(s) of the original questionnaire

Chaudhuri KR, Schapira AHV, Martinez-Martin P, et al. Can We Improve The Holistic Assessment of Parkinson’s Disease? The development of a non-motor symptom questionnaire and scale for Parkinson’s disease. ACNR 2004 Sep/Oct; 4(4):20-25 (Full Text Article)

Chaudhuri KR, Martinez-Martin P, Schapira AH, et al. International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study. Mov Disord. 2006 Jul;21(7):916-23 (Full Text Article)

Chaudhuri KR, Martinez-Martin P, Brown RG, et al. The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study. Mov Disord. 2007 Oct;22(13):1901-11 (PubMed Abstract)

Martinez-Martin P, Rodriguez-Blazquez C,  Abe K, et al. International study on the psychometric attributes of the non-motor symptoms scale in Parkinson disease. Neurology. 2009 Nov;73(19):1584-91 (Full Text Article)

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