Pediatric Quality of Life Inventory™ Cognitive Functioning Scale™ (PedsQL™ Cognitive Functioning Scale™)

Varni JW


Last update: February 2017

Basic description

Conditions of use

The PedsQL™ Cognitive Functioning Scale™ is a specific module of the PedsQL™

Existing versions: Acute version and Standard version, for Toddlers (2-4 years of age), Young Child (5-7 years of age), Child (8-12 years of age), Adolescent (13-18 years of age), Young Adult (18-25 years of age) and Adults (>26 years of age) 


Varni JW

Copyright © 1998 JW Varni, Ph.D. All rights reserved
The PedsQL™ Cognitive Functioning Scale was designed as a generic symptom-specific instrument to measure cognitive functioning in patients with acute and chronic health conditions as well as healthy school and community populations
Therapeutic area
  • Generic
Therapeutic indication


Type of Clinical Outcome Assessment (COA)
  • obsro ObsRO
  • pro PRO
Original language(s)
  • English for the USA
Bibliographic reference(s) of the original questionnaire

Varni, J.W., Limbers, C.A., Sorensen, L.G., Neighbors, K., Martz, K., Bucuvalas, J.C., & Alonso, E.M. (2011). PedsQL™ Cognitive Functioning Scale in pediatric liver transplant recipients: Feasibility, reliability and validity. Quality of Life Research, 20, 913–921.

Varni, J.W., Handen, B.L., Corey-Lisle, P.K., Guo, Z., Manos, G., Ammerman, D.K., Marcus, R.N., Owen, R., McQuade, R.D., Carson, W.H., Mathew, S., & Mankoski, R. (2012). Effect of Aripiprazole 2 to 15 mg/d on health-related quality of life in the treatment of irritability associated with Autistic Disorder in children: A post hoc analysis of two controlled trials. Clinical Therapeutics, 34, 980-992.

Swanson, J.O., Vavilala, M.S., Wang, J., Pruthi, S., Fink, J., Jaffe, K.M., Durbin, D., Koepsell, T., Temkin, N., & Rivara, F.P. (2012). Association of initial CT findings with quality-of-life outcomes for traumatic brain injury in children. Pediatric Radiology, 42, 974–981.

O’Keeffe, F., Ganesan, V., King, J., & Murphy, T. (2012). Quality-of-life and psychosocial outcome following childhood arterial ischaemic stroke. Brain Injury, 26, 1072–1083.

Limbers, C.A., Heffer, R.W., & Varni, J.W. (2009). Health-related quality of life and cognitive functioning from the perspective of parents of school-aged children with Asperger's Syndrome utilizing the PedsQL™. Journal of Autism and Developmental Disorders, 39, 1529-1541.

McCarthy, M.L., MacKenzie, E.J., Durbin, D.R., Aitken, M.E., Jaffe, K.M., Paidas, C.N. et al. (2005). The Pediatric Quality of Life Inventory: An evaluation of its reliability and validity for children with traumatic brain injury. Archives of Physical Medicine and Rehabilitation, 86, 1901-1909.

Varni JW, Beaujean AA, Limbers CA. (2013) Factorial invariance of pediatric patient self-reported fatigue across age and gender: a multigroup confirmatory factor analysis approach utilizing the PedsQL™ Multidimensional Fatigue Scale. Quality of Life Research, 22:2581–2594.

Varni JW, Burwinkle TM, Katz ER, Meeske K, Dickinson P. (2002) The PedsQL™ in pediatric cancer: reliability and validity of the Pediatric Quality of Life Inventory™ Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer. Apr 1;94(7):2090-106

Panepinto, J.A., Torres, S., Bendo, C.B., McCavit, T.L., Dinu, B., Sherman-Bien, S., Bemrich-Stolz, C., & Varni, J.W. (in press). PedsQL™ Multidimensional Fatigue Scale in sickle cell disease: Feasibility, reliability and validity. Pediatric Blood & Cancer.

Varni JW, Limbers CA. (2008). The PedsQL™ Multidimensional Fatigue Scale in young adults: feasibility, reliability and validity in a University student population. Qual Life Res. Feb;17(1):105-14